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Acne Fulminans
What is acne fulminans?
Acne fulminans is a severe form of inflammatory acne that
affects teenage boys. It has an acute onset and is marked by cystic
lesions with ulceration distributed on the trunk. Comedones and
non-inflammatory lesions are absent. Systemic symptoms are present,
including fever, fatigue, arthralgias, leukocytosis, and an elevated erythrocyte
sedimentation rate. Splonomegaly, erythema
nodosum, and aseptic osteolysis can complicate the picture.
With what can acne fulminans be confused?
Cystic acne,
acne conglobata and pyoderma faciale
should be considered in the differential diagnosis.
How is acne fulminans diagnosed?
A typical clinical picture supported by the laboratory
abnormalities mentioned above. Bone lesions are common, with lytic lesions
apparent on radiographs.
How is acne fulminans treated?
Acne fulminans fails to respond to antibacterial therapy.
Systemic steroids, tapered over several
weeks, followed by isotretinoin is
required. Standard wound care and NSAIDs are helpful as well. TNF-alpha
inhibitors, specifically infliximab, may
be useful in some patients.
Buy
Discounted Drugs
What is the prognosis for acne fulminans?
Most patients respond to treatment, though scarring and
psychological trauma are common.
What's new in acne fulminans?
Date created 04/15/2007
Last updated
01/03/2009
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